About NIAID Bioinformatics Resource Centers

The Bioinformatics Resource Centers (BRCs) for Infectious Diseases program was initiated in 2004 with the main objective of providing public access to computational platforms and analysis tools that enable collecting, archiving, updating, and integrating a variety of genomics and related research data relevant to infectious diseases, and pathogens and their interaction with hosts.

Contact

For information on flu and other viral taxa, contact IRD, ViPR (respectively)

For information on bacterial taxa, contact help@patricbrc.org

For information on protozoan & fungal taxa, or arthropod & mammalian hosts, contact help@veupathdb.org

Main Areas of Focus

The overarching goal of the BRC program is to ensure that high quality, large-scale datasets are readily Findable, Accessible, Interoperable, and Reusable (FAIR), expediting both discovery and translational research. We aim to:

  • store, update, integrate, display, and facilitate interrogation of diverse data and associated metadata, including (but not limited to) information on: genome sequence and annotation, functional genomics information (transcriptomics, proteomics, etc.), population variation, genotype/phenotype association, metagenomics, epidemiology, surveillance, antimicrobial resistance, host responses & host-pathogen interactions, etc.
  • make available analytical resources, bioinformatics tools, workspaces and services for data analysis, and provide bioinformatics training to ensure effective use of these resources
  • respond rapidly to new and emerging pandemic threats
Targeted Pathogens

Each BRC specializes in a different group of pathogens. Pathogens examined by the BRCs include, but are not limited to, those in the NIAID list of emerging and re-emerging infectious diseases. The BRCs specialize in the following groups of pathogens:

Bacterial and Viral Bioinformatics Resource Center (BV-BRC)Principal Investigators
  • Rick Stevens, Univsity of Chicago
  • Richard Scheuermann, J. Craig Venter Institute
IRD
ViPR		Human viral families including influenza virus
PATRICPathogenic bacteria and related species
Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB)Principal Investigators
  • David S. Roos, University of Pennsylvania
  • Jessica C. Kissinger, University of Georgia
  • Mary Ann McDowell, University of Notre Dame
Eukaryotic human pathogen species including fungi and protists
VectorBaseInvertebrate vectors of human pathogens including insects, arachnids, and gastropods
HostDBVertebrate hosts
OrthoMCLOrtholog groups of protein sequences
Website Usage
BV-BRC Stats
VEuPathDB Stats